Global Actinic Keratosis Trends 2025, Forecast To 2034
26 Mar, 2025
What Has Been The Evolution of the Actinic Keratosis Market in Recent Years?
The actinic keratosis market has seen considerable growth due to a variety of factors.
• In recent times, the market size for actinic keratosis has seen consistent growth. It is projected to increase from $7.95 billion in 2024 to $8.44 billion in 2025, with a compound annual growth rate (CAGR) of 6.1%.
The growth observed in the past can be linked to factors such as heightened exposure to UV radiation, an aging populace, increased awareness regarding skin cancer, more instances of actinic keratosis, development in healthcare infrastructure, surplus disposable incomes, governmental support initiatives, and a heightened emphasis on preventative skin care.
What Is the Forecasted Market Size and Growth Rate for The Actinic Keratosis Template Market?
The actinic keratosis market is expected to maintain its strong growth trajectory in upcoming years.
• Predictions suggest a remarkable surge in the market scale of actinic keratosis in the coming years. It is projected to reach a worth of $10.58 billion by 2029, with a compound annual growth rate (CAGR) of 7.4%.
This predicted growth may be due to the introduction of novel therapies, advancements in AI-enabled diagnostic instruments, an increase in combined treatment adoption, higher demand for non-invasive methods, the rising usage of tele dermatology, broader photodynamic therapy applications, a heightened understanding of cosmetic results, the advent of specific biologic therapies, rising healthcare investments in upcoming markets and an intensified focus on early detection and prevention. Leading trends expected in the projected period comprise AI-aided diagnostic instruments, machine learning for lesion examination, superior photodynamic therapy systems, wearable devices to monitor UV, nanotech-based medicine delivery, 3D imaging for tailor-made treatments, portable phototherapy devices for home use, biosensors for premature detection, software for automated lesion categorization and hydrogel-based therapeutic systems.
What Factors Are Driving Growth In The Actinic Keratosis Market?
The actinic keratosis market is projected to expand due to the escalating instances of severe sunburns. Intense skin burns, namely severe sunburns, are caused by excessive ultraviolet (UV) radiation exposure, leading to symptoms such as redness, pain, swelling, and occasionally, blistering. Sunburns result from various factors including extended exposure to ultraviolet (UV) radiation, insufficient sun protection measures, increased outdoor activities during peak UV hours, and rising temperatures due to climate change. Sunburns contribute to actinic keratosis by damaging the skin cells' DNA via ultraviolet (UV) radiation. This damage can lead to mutations that hinder normal cell functioning, subsequently leading to the formation of precancerous lesions, particularly with continuous or extended sun exposure. For instance, Melanoma Focus, a UK-based charity, revealed in May 2024 that there were 201 hospital admissions due to sunburn in 2022-23, which included 89 children and 25 babies below one year old. The organization also discovered that 66% of British adults aged 16-65 recalled getting sunburned as children, with 65% of them suffering severe sunburn with blisters at least once. This percentage increased to 77% for individuals with light, pale, or white skin. Hence, the escalating instances of severe sunburns are bolstering the growth of the actinic keratosis market.
What Are The Main Segments Of The Global Actinic Keratosis Market?
The actinic keratosis market covered in this report is segmented –
1) By Treatment Type: Topical Treatment, Surgical Procedure, Photodynamic Therapy, Other Treatment Types
2) By Distribution Channels: Hospital Pharmacies, Drug Stores And Retail Pharmacies, Online Providers
3) By End-User: Hospitals, Dermatology Clinics, Spas And Rejuvenation Centers, Homecare Settings, Other End-Users
Subsegments:
1) By Topical Treatment: 5-Fluorouracil (5-FU), Imiquimod, Diclofenac, Ingenol Mebutate, Retinoids
2) By Surgical Procedure: Cryotherapy, Curettage And Electrodessication, Excision
3) By Photodynamic Therapy: Aminolevulinic Acid (ALA) Plus Light Therapy, Methyl Aminolevulinate (MAL) Plus Light Therapy
4) By Other Treatment Types: Laser Therapy, Chemical Peels, Combination Therapies
What Emerging Trends Are Influencing The Growth Of The Actinic Keratosis Market?
Leading businesses in the actinic keratosis market are focusing their efforts on the creation of topical ointments. The intention is to effectively target and eradicate precancerous lesions, lower the chances of recurrence and boost patient adherence through shorter treatment periods and enhanced safety standards. Topical ointments, typically medicated creams or gels, are applied straight onto the relevant skin areas. They contain active components like tirbanibulin that target abnormal keratinocytes to address precancerous lesions. For example, in June 2024, the biopharmaceutical firm Almirall SA, based in Spain, gained approval from the US Food and Drug Administration (FDA) for a supplemental new drug application (sNDA) to extend the use of its drug, Klisyri, to cover an area of up to 100 cm2. This 1% tirbanibulin ointment, Klisyri, is a microtubule inhibitor purposed to hinder the growth of abnormal keratinocytes, thus effectively reducing the quantity and size of precancerous lesions in actinic keratosis (AK) treatment covering the face or scalp.
Who Are the Key Players In The Actinic Keratosis Market?
Major companies operating in the actinic keratosis market are:
• Pfizer Inc.
• F. Hoffmann-La Roche AG
• Merck & Co. Inc.
• AbbVie Inc.
• Sanofi S.A.
• Bristol-Myers Squibb
• Novartis AG
• GSK plc
• Amgen Inc.
• Bausch Health Companies Inc.
• Perrigo Company plc
• Galderma SA. Incyte Corporation
• Leo Pharma Inc.
• Almirall S.A.
• Athenex Inc.
• G&E Herbal Biotechnology Co. Ltd.
• Aclaris Therapeutics Inc.
• Biofrontera Inc.
• Hill Dermaceuticals Inc.
What Is The Most Dominant Region In The Actinic Keratosis Market?
North America was the largest region in the actinic keratosis market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the actinic keratosis market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.